You should not breast-feed while taking amoxicillin, clarithromycin, and omeprazole. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Each dose of this combination medication contains 4 pills 3 capsules and 1 tablet. Take all 4 pills twice daily before you eat, unless your doctor tells you otherwise.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. This medicine will not treat a viral infection such as the flu or a common cold. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using amoxicillin, clarithromycin, and omeprazole. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.
Do not take two doses at one time. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
Get emergency medical help if you have signs of an allergic reaction hives, difficult breathing, swelling in your face or throat or a severe skin reaction fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling. Taking amoxicillin, clarithromycin, and omeprazole long-term may cause you to develop stomach growths called fundic gland polyps.
Talk with your doctor about this risk. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Hamamoto Y. Fixed drug eruption due to clarithromycin. Gangemi S. Immediate reaction to clarithromycin. Masia M. Fulminant hepatitis and fatal toxic epidermal necrolysis Lyell disease coincident with clarithromycin administration in an alcoholic patient receiving disulfiram.
Borras-Blasco J. Henoch-Schonlein purpura associated with clarithromycin. Case report and review of literature. Terzano C. Clarithromycin and pulmonary infiltration with eosinophilia.
Baz K. Fatal aplastic anaemia in a patient with clarithromycin-induced toxic epidermal necrolysis. Ohnishi H. Clarithromycin-induced eosinophilic pneumonia. Alonso J. Fixed drug eruption on the tongue due to clarithromycin.
Khaldi N. Toxic epidermal necrolysis and clarithromycin. Can J. Dore J. Morbidity and mortality of mucocutaneous diseases in the pediatric population at a tertiary care center. Burn Care Res. Clayton T. Clarithromycin suspension-associated toxic epidermal necrolysis in a 2-year-old girl.
Lange L. Questionnaire-based survey of lifetime-prevalence and character of allergic drug reactions in German children. Pediatr Allergy Immunol. Ben-Shoshan M. Anaphylactic reaction to clarithromycin in a child. Mori F. Sensitivity and specificity of skin tests in the diagnosis of clarithromycin allergy. Swamy N. Successful clarithromycin desensitization in a multiple macrolide-allergic patient.
Mittmann N. Incidence of toxic epidermal necrolysis and Stevens-Johnson Syndrome in an HIV cohort: An observational, retrospective case series study. Petitto J. Successful clarithromycin desensitization in a macrolide-sensitive pediatric patient. Malkarnekar S. Barni S. Azithromycin is more allergenic than clarithromycin in children with suspected hypersensitivity reaction to macrolides. Blair P. DRESS syndrome presenting after initiation of mycobacterium avium complex osteomyelitis treatment.
Guvenir H. Proven Non-beta-LactAm. Antibiotic Allergy in Children. Allergy Immunol. Trevisi P. Toxic pustuloderma associated with azithromycin.
Naldi L. Cutaneous reactions to drugs. An analysis of spontaneous reports in four Italian regions. Schissel D. Azithromycin eruption in infectious mononucleosis: A proposed mechanism of Interaction. Cascaval R. Hypersensitivity syndrome associated with azithromycin. Dakdouki G. Azithromycin-induced rash in infectious mononucleosis.
Scand J. Taylor W. Tolerability of azithromycin as malaria prophylaxis in adults in northeast papua, indonesia. Agents Chemother. Odemis E. Azithromycin-induced leukocytoclastic vasculitis. Aihara Y. Stevens-Johnson syndrome associated with azithromycin followed by transient reactivation of herpes simplex virus infection.
Noel M. Cutaneous adverse drug reactions in hospitalized patients in a tertiary care center. Indian J. Brkljacic N. Stevens-Johnson syndrome as an unusual adverse effect of azithromycin. Cummings J. Drug-induced linear immunoglobulin A bullous dermatosis mimicking Stevens-Johnson syndrome: A case report.
Pursnani A. Hypersensitivity myocarditis associated with azithromycin exposure. Flavia Monteagudo Paz A. Allergic contact dermatitis caused by azithromycin in an eye drop. Bauer K. Pediatric Derm. Azithromycin anaphylaxis in children. Banerjee I. Azithromycin-induced rash in a patient of infectious mononucleosis—A case report with review of literature.
Mendes-Bastos P. Non-occupational allergic contact dermatitis caused by azithromycin in an eye solution. Sriratanaviriyakul N. Drug reaction with eosinophilia and Systemic symptoms syndrome DRESS syndrome associated with azithromycin presenting like septic shock: A case report. Case Rep. Da Cunha Filho R. Acute generalized exanthematous pustulosis by azithromycin. Das A. Azithromycin induced bullous fixed drug eruption.
Nappe T. Stevens-Johnson syndrome after treatment with azithromycin: An uncommon culprit. Campanon-Toro M. Acute generalized exanthematous pustulosis AGEP induced by azithromycin. Kobayashi A. An infant case of severe hypereosinophilia and Systemic symptoms with multiple drug hypersensitivity and reactivation of cytomegalovirus and BK virus. Fixed drug eruption probably induced by azithromycin. Australas J. Nursing care of a boy seriously infected with Steven-Johnson syndrome after treatment with azithromycin: A case report and literature review.
Medicine Baltimore ; 97 :e Iarikov D. Hypersensitivity reactions associated with fidaxomicin use. Park J. Multiple antibiotic sensitivity syndrome in children. Messaad D. Drug provocation tests in patients with a history suggesting an immediate drug hypersensitivity reaction. Support Center Support Center. External link. Please review our privacy policy. Anaphylaxis [ 19 ]. Urticaria [ 20 ]. MPR [ 21 ]. MPR [ 22 ]. Anaphylaxis dyspnea, laryngeal edema [ 23 ]. HSP [ 24 ]. FDE [ 25 ]. Urticaria [ 26 ].
Cholestatic hepatitis [ 27 ]. MPR [ 28 ] Hepatotoxicity. Rash [ 29 ]. Rash [ 30 ]. Cholestatic hepatitis [ 31 ]. MPR [ 32 ]. SJS [ 33 ]. Hepatotoxicity [ 34 ]. Interstitial Nephritis [ 36 ]. Rash [ 37 ]. Cholestatic hepatitis [ 38 ]. FDE [ 39 ]. TEN [ 40 ]. Granulomatous interstitial nephritis [ 41 ]. Y staggered phenylpropanolamine and amoxicillin. Cholestatic hepatitis [ 42 ]. MPE [ 43 ].
TEN [ 44 ]. FDE [ 45 ]. MAS [ 46 ]. MPE [ 47 ]. Y same reaction with spiramycin 1 yr prior. FDE [ 48 ]. MPE, pruritus, fever, hepatitis [ 49 ]. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Tell your doctor about all your current medicines. Many drugs can affect amoxicillin, clarithromycin, and lansoprazole, especially:.
This list is not complete and many other drugs may affect amoxicillin, clarithromycin, and lansoprazole.
This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here. Your pharmacist can provide more information about amoxicillin, clarithromycin, and lansoprazole.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc.
Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use.
Learn how we develop our content. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.
Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed. It is very important that your doctor check the progress of you or your child at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects. If you or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor. This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention.
Call your doctor right away if you or your child have a rash, itching, hives, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after you take this medicine. Serious skin reactions can occur with this medicine. Check with your doctor right away if you or your child have blistering, peeling, or loosening of the skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine.
Check with your doctor right away if you or your child have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These could be symptoms of a serious liver problem. Call your child's doctor right away if your child feels irritable or vomits after feeding. These may be symptoms of a condition called infantile hypertrophic pyloric stenosis. Azithromycin may cause diarrhea, and in some cases it can be severe.
It may occur 2 months or more after you stop using this medicine. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you or your child have any questions about this or if mild diarrhea continues or gets worse, check with your doctor. This medicine can cause changes in heart rhythms, such as a condition called QT prolongation.
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